Non-infectious Panniculitis during Hydroxyurea Therapy in a Patient with Myeloproliferative Disease.
نویسندگان
چکیده
منابع مشابه
Successful treatment of hydroxyurea-associated panniculitis and vasculitis with low-dose methotrexate
INTRODUCTION Hydroxyurea is a standard treatment for myeloproliferative disorders because of its cytoreductive effects on all bone marrow cell lines. As a hydroxylated derivative of urea, it inhibits DNA synthesis by inactivating ribonucleotide diphosphate reductase. Hydroxyurea is generally well tolerated. However, a variety of cutaneous side effects including leg ulcers, dermatomyositis, and ...
متن کاملReversible leg ulcer due to hydroxyurea in a case of chronic myeloid leukemia.
The cutaneous side effects of hydroxyurea are lesser known complication of long term hydroxyurea therapy in myeloproliferative disorders. We report a non-diabetic patient, who developed hydroxyurea dermopathy (leg ulcers) during long-term treatment with hydroxyurea for chronic myeloid leukemia (CML). The time course of the development of ulcers and its healing suggests that these resulted from ...
متن کاملSecond malignancies in philadelphia-negative myeloproliferative neoplasms-single-center experience.
AIM The aim of this work was to retrospectively analyze patients with Philadelphia-negative myeloproliferative neoplasms through evaluation of frequency and characteristics of second malignancies (other than acute leukaemia and myelodysplastic syndrome). PATIENTS AND METHODS Records of 172 patients were reviewed; an analysis was performed on data from 66 patients treated with hydroxyurea, 105...
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Background: Hydroxyurea (HU) is a well known chemotherapeutic agent that has been used largely for various myeloproliferative diseases over the past 20 years. In β-thalassemia, the effect of HU is much less clear and remains controversial. This study was undertaken to describe the hematologic and clinical responses of thalassemia major and intermediate patients to HU treatment during 2 years. M...
متن کاملSuccessful treatment of hydroxyurea-associated chronic leg ulcers associated with squamous cell carcinoma.
Hydroxyurea (HU) is an antineoplastic drug used in the treatment of chronic myeloproliferative neoplasms (MPNs). HU is associated with cutaneous adverse effects, whereas severe complications such as leg ulcers and non-melanoma skin cancers (NMSCs) are rare and only observed after long-term treatment. We herein report a patient with essential thrombocythemia (ET) treated chronically with HU, and...
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عنوان ژورنال:
- Acta dermato-venereologica
دوره 96 4 شماره
صفحات -
تاریخ انتشار 2016